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Airway IL-1β associates with IL-5 production following dust mite allergen inhalation in humans

BACKGROUND: Preclinical studies implicate interleukin (IL)-1β as a key mediator of asthma and have shown the efficacy of IL-1 antagonism for treatment of allergic airway inflammation; human studies in this area are lacking. OBJECTIVES: Our aim was to study the relationship of airway IL-1β to feature...

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Detalles Bibliográficos
Autores principales: Burbank, Allison J., Schworer, Stephen A., Sood, Amika, Almond, Martha, Chason, Kelly, Bean, Nathan, Zhou, Haibo, Hernandez, Michelle L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8649318/
https://www.ncbi.nlm.nih.gov/pubmed/34876117
http://dx.doi.org/10.1186/s12931-021-01903-9