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FunGraph: A statistical protocol to reconstruct omnigenic multilayer interactome networks for complex traits

We describe a statistical protocol of how to reconstruct and dissect functional omnigenic multilayer interactome networks that mediate complex dynamic traits in a genome-wide association study (GWAS). This protocol, named FunGraph, can analyze how each locus affects phenotypic variation through its...

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Detalles Bibliográficos
Autores principales: Dong, Ang, Feng, Li, Yang, Dengcheng, Wu, Shuang, Zhao, Jinshuai, Wang, Jing, Wu, Rongling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8649398/
https://www.ncbi.nlm.nih.gov/pubmed/34927094
http://dx.doi.org/10.1016/j.xpro.2021.100985