Pericardial Adipose Tissue–Derived Leptin Promotes Myocardial Apoptosis in High‐Fat Diet–Induced Obese Rats Through Janus Kinase 2/Reactive Oxygen Species/Na+/K+‐ATPase Signaling Pathway

BACKGROUND: Pathophysiologic mechanisms underlying cardiac structural and functional changes in obesity are complex and linked to adipocytokines released from pericardial adipose tissue (PAT) and cardiomyocyte apoptosis. Although leptin is involved in various pathological conditions, its role in par...

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Detalles Bibliográficos
Autores principales: Wang, Ping, Luo, Chaodi, Zhu, Danjun, Song, Yan, Cao, Lifei, Luan, Hui, Gao, Lan, Zheng, Shuping, Li, Hao, Tian, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8649551/
https://www.ncbi.nlm.nih.gov/pubmed/34482701
http://dx.doi.org/10.1161/JAHA.121.021369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8649551/
https://www.ncbi.nlm.nih.gov/pubmed/34482701
http://dx.doi.org/10.1161/JAHA.121.021369

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