Cargando…
Pericardial Adipose Tissue–Derived Leptin Promotes Myocardial Apoptosis in High‐Fat Diet–Induced Obese Rats Through Janus Kinase 2/Reactive Oxygen Species/Na+/K+‐ATPase Signaling Pathway
BACKGROUND: Pathophysiologic mechanisms underlying cardiac structural and functional changes in obesity are complex and linked to adipocytokines released from pericardial adipose tissue (PAT) and cardiomyocyte apoptosis. Although leptin is involved in various pathological conditions, its role in par...
Autores principales: | Wang, Ping, Luo, Chaodi, Zhu, Danjun, Song, Yan, Cao, Lifei, Luan, Hui, Gao, Lan, Zheng, Shuping, Li, Hao, Tian, Gang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8649551/ https://www.ncbi.nlm.nih.gov/pubmed/34482701 http://dx.doi.org/10.1161/JAHA.121.021369 |
Ejemplares similares
-
Elevated 1-h postload plasma glucose levels identify coronary heart disease patients with greater severity of coronary artery lesions and higher risk of 1-year re-admission
por: Cao, Lifei, et al.
Publicado: (2020) -
pNaKtide inhibits Na/K-ATPase reactive oxygen species amplification and attenuates adipogenesis
por: Sodhi, Komal, et al.
Publicado: (2015) -
The Na/K-ATPase Signaling: From Specific Ligands to General Reactive Oxygen Species
por: Pratt, Rebecca D., et al.
Publicado: (2018) -
Epicardial Adipose Tissue–Derived Leptin Promotes Myocardial Injury in Metabolic Syndrome Rats Through PKC/NADPH Oxidase/ROS Pathway
por: Chen, Hui, et al.
Publicado: (2023) -
Adiposity, leptin and stress reactivity in humans
por: Brydon, Lena
Publicado: (2011)