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SPAK Deficiency Attenuates Chemotherapy-Induced Intestinal Mucositis

INTRODUCTION: Ste20-related protein proline/alanine-rich kinase (SPAK) affects cell proliferation, differentiation, and transformation, and sodium and chloride transport in the gut. However, its role in gut injury pathogenesis is unclear. OBJECTIVE: We determined the role of SPAK in chemotherapy-ind...

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Detalles Bibliográficos
Autores principales: Huang, Tien-Yu, Yang, Sung-Sen, Liao, Ching-Len, Lin, Ming-Hong, Lin, Hsuan-Hwai, Lin, Jung-Chun, Chen, Peng-Jen, Shih, Yu-Lueng, Chang, Wei-Kuo, Hsieh, Tsai-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8649624/
https://www.ncbi.nlm.nih.gov/pubmed/34888232
http://dx.doi.org/10.3389/fonc.2021.733555