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The Retropepsin-Type Protease APRc as a Novel Ig-Binding Protein and Moonlighting Immune Evasion Factor of Rickettsia

Rickettsiae are obligate intracellular Gram-negative bacteria transmitted by arthropod vectors. Despite their reduced genomes, the function(s) of the majority of rickettsial proteins remains to be uncovered. APRc is a highly conserved retropepsin-type protease, suggested to act as a modulator of oth...

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Detalles Bibliográficos
Autores principales: Curto, Pedro, Barro, Andreia, Almeida, Carla, Vieira-Pires, Ricardo S., Simões, Isaura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8649778/
https://www.ncbi.nlm.nih.gov/pubmed/34872352
http://dx.doi.org/10.1128/mBio.03059-21