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The Inhibitory Effect of Curcumin Derivative J147 on Melanogenesis and Melanosome Transport by Facilitating ERK-Mediated MITF Degradation

The therapeutic use of curcumin and chemically modified curcumin (CMC) for suppressing melanogenesis and tyrosinase activity have been recognized. J147 is a modified version of curcumin with superior bioavailability and stability. However, there is no report about the effects of J147 on pigmentation...

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Detalles Bibliográficos
Autores principales: Lv, Jinpeng, Yang, Ying, Jia, Bingyi, Li, Siqi, Zhang, Ximei, Gao, Rongyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8649847/
https://www.ncbi.nlm.nih.gov/pubmed/34887767
http://dx.doi.org/10.3389/fphar.2021.783730