Neonatal neuronal WWOX gene therapy rescues Wwox null phenotypes

WW domain‐containing oxidoreductase (WWOX) is an emerging neural gene‐regulating homeostasis of the central nervous system. Germline biallelic mutations in WWOX cause WWOX‐related epileptic encephalopathy (WOREE) syndrome and spinocerebellar ataxia and autosomal recessive 12 (SCAR12), two devastatin...

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Detalles Bibliográficos
Autores principales: Repudi, Srinivasarao, Kustanovich, Irina, Abu‐Swai, Sara, Stern, Shani, Aqeilan, Rami I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8649866/
https://www.ncbi.nlm.nih.gov/pubmed/34747138
http://dx.doi.org/10.15252/emmm.202114599

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8649866/
https://www.ncbi.nlm.nih.gov/pubmed/34747138
http://dx.doi.org/10.15252/emmm.202114599

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