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Biallelic mutations in MOS cause female infertility characterized by human early embryonic arrest and fragmentation

Early embryonic arrest and fragmentation (EEAF) is a common phenomenon leading to female infertility, but the genetic determinants remain largely unknown. The Moloney sarcoma oncogene (MOS) encodes a serine/threonine kinase that activates the ERK signaling cascade during oocyte maturation in vertebr...

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Detalles Bibliográficos
Autores principales: Zhang, Yin‐Li, Zheng, Wei, Ren, Peipei, Hu, Huiling, Tong, Xiaomei, Zhang, Shuo‐Ping, Li, Xiang, Wang, Haichao, Jiang, Jun‐Chao, Jin, Jiamin, Yang, Weijie, Cao, Lanrui, He, Yuanlin, Ma, Yerong, Zhang, Yingyi, Gu, Yifan, Hu, Liang, Luo, Keli, Gong, Fei, Lu, Guang‐Xiu, Lin, Ge, Fan, Heng‐Yu, Zhang, Songying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8649871/
https://www.ncbi.nlm.nih.gov/pubmed/34779126
http://dx.doi.org/10.15252/emmm.202114887