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Biallelic mutations in MOS cause female infertility characterized by human early embryonic arrest and fragmentation
Early embryonic arrest and fragmentation (EEAF) is a common phenomenon leading to female infertility, but the genetic determinants remain largely unknown. The Moloney sarcoma oncogene (MOS) encodes a serine/threonine kinase that activates the ERK signaling cascade during oocyte maturation in vertebr...
Autores principales: | Zhang, Yin‐Li, Zheng, Wei, Ren, Peipei, Hu, Huiling, Tong, Xiaomei, Zhang, Shuo‐Ping, Li, Xiang, Wang, Haichao, Jiang, Jun‐Chao, Jin, Jiamin, Yang, Weijie, Cao, Lanrui, He, Yuanlin, Ma, Yerong, Zhang, Yingyi, Gu, Yifan, Hu, Liang, Luo, Keli, Gong, Fei, Lu, Guang‐Xiu, Lin, Ge, Fan, Heng‐Yu, Zhang, Songying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8649871/ https://www.ncbi.nlm.nih.gov/pubmed/34779126 http://dx.doi.org/10.15252/emmm.202114887 |
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