The Aza-Prins Reaction of 1,2-Dicarbonyl Compounds with 3-Vinyltetrahydroquinolines: Application to the Synthesis of Polycyclic Spirooxindole Derivatives

[Image: see text] The aza-Prins reaction of 6,7-dimethoxy-3-vinyl-1,2,3,4-tetrahydroquinoline (1) with 1,2-dicarbonyl compounds proceeded smoothly in the presence of HCl, and the corresponding tricyclic benzazocines were isolated in yields of 20–86%. The reaction proceeded in a stereoselective manne...

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Detalles Bibliográficos
Autores principales: Saito, Shinichi, Katamura, Tomohiro, Tsukazaki, Rei, Fujisawa, Akito, Yoshigoe, Yusuke, Mutoh, Yuichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650011/
https://www.ncbi.nlm.nih.gov/pubmed/34792347
http://dx.doi.org/10.1021/acs.joc.1c01785

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650011/
https://www.ncbi.nlm.nih.gov/pubmed/34792347
http://dx.doi.org/10.1021/acs.joc.1c01785

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