Pulsatile Bi-Directional Aerosol Flow Affects Aerosol Delivery to the Intranasal Olfactory Region: A Patient-Specific Computational Study

The nasal olfactory region is a potential route for non-invasive delivery of drugs directly from the nasal epithelium to the brain, bypassing the often impermeable blood-brain barrier. However, efficient aerosol delivery to the olfactory region is challenging due to its location in the nose. Here we...

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Detalles Bibliográficos
Autores principales: Farnoud, Ali, Tofighian, Hesam, Baumann, Ingo, Martin, Andrew R., Rashidi, Mohammad M., Menden, Micheal P., Schmid, Otmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650014/
https://www.ncbi.nlm.nih.gov/pubmed/34887754
http://dx.doi.org/10.3389/fphar.2021.746420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650014/
https://www.ncbi.nlm.nih.gov/pubmed/34887754
http://dx.doi.org/10.3389/fphar.2021.746420

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