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A novel model of a biomechanically induced osteoarthritis‐like cartilage for pharmacological in vitro studies

Excessive pressure or overload induces and aggravates osteoarthritic changes in articular cartilage, but the underlying biomechanical forces are largely ignored in existing pharmacological in vitro models that are used to investigate drugs against osteoarthritis (OA). Here, we introduce a novel in v...

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Detalles Bibliográficos
Autores principales: Sauerland, Katrin, Wolf, Amela, Schudok, Manfred, Steinmeyer, Juergen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650028/
https://www.ncbi.nlm.nih.gov/pubmed/34766430
http://dx.doi.org/10.1111/jcmm.17044