Normothermic machine perfusion attenuates hepatic ischaemia‐reperfusion injury by inhibiting CIRP‐mediated oxidative stress and mitochondrial fission

Extracellular cold‐inducible RNA‐binding protein (CIRP) is a proinflammatory mediator that aggravates ischaemia‐reperfusion injury (IRI). Normothermic machine perfusion (NMP) could effectively alleviate the IRI of the liver, but the underlying mechanism remains to be explored. We show that human DCD...

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Detalles Bibliográficos
Autores principales: Liu, Wenyan, Fan, Yang, Ding, Hongfan, Han, Dan, Yan, Yang, Wu, Rongqian, Lv, Yi, Zheng, Xinglong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650030/
https://www.ncbi.nlm.nih.gov/pubmed/34786826
http://dx.doi.org/10.1111/jcmm.17062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650030/
https://www.ncbi.nlm.nih.gov/pubmed/34786826
http://dx.doi.org/10.1111/jcmm.17062

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