Pharmacological inhibition of Carbonic Anhydrase IX and XII to enhance targeting of acute myeloid leukaemia cells under hypoxic conditions

Acute myeloid leukaemia (AML) is an aggressive form of blood cancer that carries a dismal prognosis. Several studies suggest that the poor outcome is due to a small fraction of leukaemic cells that elude treatment and survive in specialised, oxygen (O(2))‐deprived niches of the bone marrow. Although...

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Detalles Bibliográficos
Autores principales: Chen, Fangli, Licarete, Emilia, Wu, Xue, Petrusca, Daniela, Maguire, Callista, Jacobsen, Max, Colter, Austyn, Sandusky, George E., Czader, Magdalena, Capitano, Maegan L., Ropa, James P., Boswell, H. Scott, Carta, Fabrizio, Supuran, Claudiu T., Parkin, Brian, Fishel, Melissa L., Konig, Heiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650039/
https://www.ncbi.nlm.nih.gov/pubmed/34791807
http://dx.doi.org/10.1111/jcmm.17027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650039/
https://www.ncbi.nlm.nih.gov/pubmed/34791807
http://dx.doi.org/10.1111/jcmm.17027

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