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Down‐regulation of MYH10 driven by chromosome 17p13.1 deletion promotes hepatocellular carcinoma metastasis through activation of the EGFR pathway

Somatic copy number alterations (CNAs) are a genomic hallmark of cancers. Among them, the chromosome 17p13.1 deletions are recurrent in hepatocellular carcinoma (HCC). Here, utilizing an integrative omics analysis, we screened out a novel tumour suppressor gene within 17p13.1, myosin heavy chain 10...

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Detalles Bibliográficos
Autores principales: Jin, Qian, Cheng, Min, Xia, Xia, Han, Yuqing, Zhang, Jing, Cao, Pengbo, Zhou, Gangqiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650048/
https://www.ncbi.nlm.nih.gov/pubmed/34738311
http://dx.doi.org/10.1111/jcmm.17036