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Computational Modelling and Big Data Analysis of Flow and Drug Transport in Microfluidic Systems: A Spheroid-on-a-Chip Study

Microfluidic tumour spheroid-on-a-chip platforms enable control of spheroid size and their microenvironment and offer the capability of high-throughput drug screening, but drug supply to spheroids is a complex process that depends on a combination of mechanical, biochemical, and biophysical factors....

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Detalles Bibliográficos
Autores principales: Kheiri, Sina, Kumacheva, Eugenia, Young, Edmond W.K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650096/
https://www.ncbi.nlm.nih.gov/pubmed/34888303
http://dx.doi.org/10.3389/fbioe.2021.781566