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Synthesis of Bis-heteroaryls Using Grignard Reagents and Pyridylsulfonium Salts
[Image: see text] Herein are reported ligand-coupling reactions of Grignard reagents with pyridylsulfonium salts. The method has wide functional group tolerance and enables the formation of bis-heterocycle linkages, including 2,4′-, 2,3′-, and 2,2′-bipyridines, as well as pyridines linked to pyrimid...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650099/ https://www.ncbi.nlm.nih.gov/pubmed/34784224 http://dx.doi.org/10.1021/acs.orglett.1c03379 |