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Synthesis of Bis-heteroaryls Using Grignard Reagents and Pyridylsulfonium Salts

[Image: see text] Herein are reported ligand-coupling reactions of Grignard reagents with pyridylsulfonium salts. The method has wide functional group tolerance and enables the formation of bis-heterocycle linkages, including 2,4′-, 2,3′-, and 2,2′-bipyridines, as well as pyridines linked to pyrimid...

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Detalles Bibliográficos
Autores principales: Horan, Alexandra M., Duong, Vincent K., McGarrigle, Eoghan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650099/
https://www.ncbi.nlm.nih.gov/pubmed/34784224
http://dx.doi.org/10.1021/acs.orglett.1c03379