RAD52: Paradigm of Synthetic Lethality and New Developments

DNA double-strand breaks and inter-strand cross-links are the most harmful types of DNA damage that cause genomic instability that lead to cancer development. The highest fidelity pathway for repairing damaged double-stranded DNA is termed Homologous recombination (HR). Rad52 is one of the key HR pr...

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Detalles Bibliográficos
Autores principales: Rossi, Matthew J., DiDomenico, Sarah F., Patel, Mikir, Mazin, Alexander V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650160/
https://www.ncbi.nlm.nih.gov/pubmed/34887904
http://dx.doi.org/10.3389/fgene.2021.780293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650160/
https://www.ncbi.nlm.nih.gov/pubmed/34887904
http://dx.doi.org/10.3389/fgene.2021.780293

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