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The asymmetric Pitx2 gene regulates gut muscular-lacteal development and protects against fatty liver disease

Intestinal lacteals are essential lymphatic channels for absorption and transport of dietary lipids and drive the pathogenesis of debilitating metabolic diseases. However, organ-specific mechanisms linking lymphatic dysfunction to disease etiology remain largely unknown. In this study, we uncover an...

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Detalles Bibliográficos
Autores principales: Hu, Shing, Mahadevan, Aparna, Elysee, Isaac F., Choi, Joseph, Souchet, Nathan R., Bae, Gloria H., Taboada, Alessandra K., Sanketi, Bhargav, Duhamel, Gerald E., Sevier, Carolyn S., Tao, Ge, Kurpios, Natasza A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650168/
https://www.ncbi.nlm.nih.gov/pubmed/34818545
http://dx.doi.org/10.1016/j.celrep.2021.110030