Repression of the expression of proinflammatory genes by mitochondrial transcription factor A is linked to its alternative splicing regulation in human lung epithelial cells

BACKGROUND: Mitochondrial transcription factor A (TFAM) is associated with a number of neurodegenerative diseases and also with asthma. TFAM deficiency-induced mitochondrial DNA stress primes the antiviral innate immune response in mouse embryonic fibroblasts. However, the role of TFAM in asthma rel...

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Detalles Bibliográficos
Autores principales: Luo, Jinsong, Liu, Hong, Li, Daniel K. Jun, Song, Bin, Zhang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650232/
https://www.ncbi.nlm.nih.gov/pubmed/34876009
http://dx.doi.org/10.1186/s12865-021-00464-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650232/
https://www.ncbi.nlm.nih.gov/pubmed/34876009
http://dx.doi.org/10.1186/s12865-021-00464-2

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