GR-mediated transcriptional regulation of m(6)A metabolic genes contributes to diet-induced fatty liver in hens

BACKGROUND: Glucocorticoid receptor (GR) mediated corticosterone-induced fatty liver syndrome (FLS) in the chicken by transactivation of Fat mass and obesity associated gene (FTO), leading to demethylation of N6-methyladenosine (m(6)A) and post-transcriptional activation of lipogenic genes. Nutritio...

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Detalles Bibliográficos
Autores principales: Feng, Yue, Li, Yanlin, Jiang, Wenduo, Hu, Yun, Jia, Yimin, Zhao, Ruqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650238/
https://www.ncbi.nlm.nih.gov/pubmed/34872591
http://dx.doi.org/10.1186/s40104-021-00642-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650238/
https://www.ncbi.nlm.nih.gov/pubmed/34872591
http://dx.doi.org/10.1186/s40104-021-00642-7

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