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GR-mediated transcriptional regulation of m(6)A metabolic genes contributes to diet-induced fatty liver in hens

BACKGROUND: Glucocorticoid receptor (GR) mediated corticosterone-induced fatty liver syndrome (FLS) in the chicken by transactivation of Fat mass and obesity associated gene (FTO), leading to demethylation of N6-methyladenosine (m(6)A) and post-transcriptional activation of lipogenic genes. Nutritio...

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Detalles Bibliográficos
Autores principales:	Feng, Yue, Li, Yanlin, Jiang, Wenduo, Hu, Yun, Jia, Yimin, Zhao, Ruqian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650238/ https://www.ncbi.nlm.nih.gov/pubmed/34872591 http://dx.doi.org/10.1186/s40104-021-00642-7

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