Tricking enzymes in living cells: a mechanism-based strategy for design of DNA topoisomerase biosensors

Most activity-based molecular probes are designed to target enzymes that catalyze the breaking of chemical bonds and the conversion of a unimolecular substrate into bimolecular products. However, DNA topoisomerases are a class of enzymes that alter DNA topology without producing any molecular segmen...

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Detalles Bibliográficos
Autores principales: Ba, Sai, Gao, Guangpeng, Li, Tianhu, Zhang, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650243/
https://www.ncbi.nlm.nih.gov/pubmed/34876137
http://dx.doi.org/10.1186/s12951-021-01155-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650243/
https://www.ncbi.nlm.nih.gov/pubmed/34876137
http://dx.doi.org/10.1186/s12951-021-01155-1

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