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GTSE1 is possibly involved in the DNA damage repair and cisplatin resistance in osteosarcoma

BACKGROUND: G2 and S phase-expressed-1 (GTSE1) negatively regulates the tumor-suppressive protein p53 and is potentially correlated with chemoresistance of cancer cells. This study aims to explore the effect of GTSE1 on the DNA damage repair and cisplatin (CDDP) resistance in osteosarcoma (OS). MATE...

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Detalles Bibliográficos
Autores principales: Xie, Chaofan, Xiang, Wei, Shen, Huiyong, Shen, Jingnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650252/
https://www.ncbi.nlm.nih.gov/pubmed/34876170
http://dx.doi.org/10.1186/s13018-021-02859-8