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GTSE1 is possibly involved in the DNA damage repair and cisplatin resistance in osteosarcoma
BACKGROUND: G2 and S phase-expressed-1 (GTSE1) negatively regulates the tumor-suppressive protein p53 and is potentially correlated with chemoresistance of cancer cells. This study aims to explore the effect of GTSE1 on the DNA damage repair and cisplatin (CDDP) resistance in osteosarcoma (OS). MATE...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650252/ https://www.ncbi.nlm.nih.gov/pubmed/34876170 http://dx.doi.org/10.1186/s13018-021-02859-8 |