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geneBasis: an iterative approach for unsupervised selection of targeted gene panels from scRNA-seq

scRNA-seq datasets are increasingly used to identify gene panels that can be probed using alternative technologies, such as spatial transcriptomics, where choosing the best subset of genes is vital. Existing methods are limited by a reliance on pre-existing cell type labels or by difficulties in ide...

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Detalles Bibliográficos
Autores principales: Missarova, Alsu, Jain, Jaison, Butler, Andrew, Ghazanfar, Shila, Stuart, Tim, Brusko, Maigan, Wasserfall, Clive, Nick, Harry, Brusko, Todd, Atkinson, Mark, Satija, Rahul, Marioni, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650258/
https://www.ncbi.nlm.nih.gov/pubmed/34872616
http://dx.doi.org/10.1186/s13059-021-02548-z