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Attenuated expression of SNF5 facilitates progression of bladder cancer via STAT3 activation

BACKGROUND: SWI/SNF, a well-known ATP-dependent chromatin-remodeling complex, plays an essential role in several biological processes. SNF5, the core subunit of the SWI/SNF remodeling complex, inactivated in 95% of malignant rhabdoid tumors (MRT), highlighting its significance in tumorigenesis. Howe...

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Detalles Bibliográficos
Autores principales: Ding, Hua, Huang, Yaqin, Shi, Jiazhong, Wang, Liwei, Liu, Sha, Zhao, Baixiong, Liu, Yuting, Yang, Jin, Chen, Zhiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650342/
https://www.ncbi.nlm.nih.gov/pubmed/34876150
http://dx.doi.org/10.1186/s12935-021-02363-3