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Abolished ketamine effects on the spontaneous excitatory postsynaptic current of medial prefrontal cortex neurons in GluN2D knockout mice

Ketamine, a non-competitive antagonist of the N-methyl-d-aspartate receptor (NMDAR), generates a rapidly-acting antidepressant effect. It exerts psychomimetic effects, yet demands a further investigation of its mechanism. Previous research showed that ketamine did no longer promote hyperlocomotion i...

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Detalles Bibliográficos
Autores principales: Han, Dae Hee, Hong, Ilgang, Choi, Ja Eun, Park, Pojeong, Baek, Jun-Yeong, Park, HyoJin, Ide, Soichiro, Mishina, Masayoshi, Ikeda, Kazutaka, Kaang, Bong-Kiun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650376/
https://www.ncbi.nlm.nih.gov/pubmed/34876180
http://dx.doi.org/10.1186/s13041-021-00883-7