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Hypercortisolism in patients with cholestasis is associated with disease severity

BACKGROUND: Cholestasis might lead to an impairment of adrenal function as suggested by in vitro and in vivo data as well as by clinical findings. Bile acid and adrenal steroid metabolism not only share the receptors farnesoid X receptor (FXR) and the G protein-coupled bile acid receptor 1 (TGR5), b...

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Detalles Bibliográficos
Autores principales: Theiler-Schwetz, Verena, Schlager, Hansjörg, Obermayer-Pietsch, Barbara, Stojakovic, Tatjana, Fauler, Günter, Fickert, Peter, Zollner, Gernot
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650422/
https://www.ncbi.nlm.nih.gov/pubmed/34876016
http://dx.doi.org/10.1186/s12876-021-02045-4