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Hepatitis B virus polymerase-specific T cell epitopes shift in a mouse model of chronic infection

BACKGROUND: Chronic hepatitis B virus (HBV) infection (CHB) is a significant public health problem that could benefit from treatment with immunomodulators. Here we describe a set of therapeutic HBV vaccines that target the internal viral proteins. METHODS: Vaccines are delivered by chimpanzee adenov...

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Detalles Bibliográficos
Autores principales: Hasanpourghadi, Mohadeseh, Novikov, Mikhail, Newman, Dakota, Xiang, ZhiQuan, Zhou, Xiang Yang, Magowan, Colin, Ertl, Hildegund C. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650432/
https://www.ncbi.nlm.nih.gov/pubmed/34876153
http://dx.doi.org/10.1186/s12985-021-01712-y