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Insulin-Like Growth Factor-1 Differentially Modulates Glutamate-Induced Toxicity and Stress in Cells of the Neurogliovascular Unit

The age-related reduction in circulating levels of insulin-like growth factor-1 (IGF-1) is associated with increased risk of stroke and neurodegenerative diseases in advanced age. Numerous reports highlight behavioral and physiological deficits in blood-brain barrier function and neurovascular commu...

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Detalles Bibliográficos
Autores principales: Hayes, Cellas A., Ashmore, Brandon G., Vijayasankar, Akshaya, Marshall, Jessica P., Ashpole, Nicole M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650493/
https://www.ncbi.nlm.nih.gov/pubmed/34887742
http://dx.doi.org/10.3389/fnagi.2021.751304