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Insulin-Like Growth Factor-1 Differentially Modulates Glutamate-Induced Toxicity and Stress in Cells of the Neurogliovascular Unit
The age-related reduction in circulating levels of insulin-like growth factor-1 (IGF-1) is associated with increased risk of stroke and neurodegenerative diseases in advanced age. Numerous reports highlight behavioral and physiological deficits in blood-brain barrier function and neurovascular commu...
Autores principales: | Hayes, Cellas A., Ashmore, Brandon G., Vijayasankar, Akshaya, Marshall, Jessica P., Ashpole, Nicole M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650493/ https://www.ncbi.nlm.nih.gov/pubmed/34887742 http://dx.doi.org/10.3389/fnagi.2021.751304 |
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