The Role of PDE11A4 in Social Isolation-Induced Changes in Intracellular Signaling and Neuroinflammation

Phosphodiesterase 11A (PDE11A), an enzyme that degrades cyclic nucleotides (cAMP and cGMP), is the only PDE whose mRNA expression in brain is restricted to the hippocampal formation. Previously, we showed that chronic social isolation changes subsequent social behaviors in adult mice by reducing exp...

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Detalles Bibliográficos
Autores principales: Pilarzyk, Katy, Farmer, Reagan, Porcher, Latarsha, Kelly, Michy P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650591/
https://www.ncbi.nlm.nih.gov/pubmed/34887755
http://dx.doi.org/10.3389/fphar.2021.749628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650591/
https://www.ncbi.nlm.nih.gov/pubmed/34887755
http://dx.doi.org/10.3389/fphar.2021.749628

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