Prostate-Specific Membrane Antigen and Esterase Dual Responsive Camptothecin–Oligopeptide Self-Assembled Nanoparticles for Efficient Anticancer Drug Delivery

BACKGROUND: The clinical utility of camptothecin (CPT) is restricted by poor aqueous solubility, high lipophilicity, active lactone ring instability, and off-targeted toxicities. We report here a prostate-specific membrane antigen (PSMA) and esterase dual responsive self-assembled nanoparticles (CPT...

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Detalles Bibliográficos
Autores principales: Xu, Bing, Yan, Mengmeng, Zhou, Fei, Cai, Desheng, Guo, Wenbo, Jia, Xiaohui, Liu, Runping, Ma, Tao, Li, Tong, Gao, Feng, Wang, Penglong, Lei, Haimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650835/
https://www.ncbi.nlm.nih.gov/pubmed/34887660
http://dx.doi.org/10.2147/IJN.S331060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650835/
https://www.ncbi.nlm.nih.gov/pubmed/34887660
http://dx.doi.org/10.2147/IJN.S331060

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