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Period 2 Regulates CYP2B10 Expression and Activity in Mouse Liver

CYP2B10 is responsible for metabolism and detoxification of many clinical drugs. Here, we aimed to investigate a potential role of Period 2 (PER2) in regulating expression of hepatic CYP2B10. Regulatory effects of PER2 on hepatic expression of CYP2B10 and other enzymes were determined using Per2-def...

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Detalles Bibliográficos
Autores principales: Chen, MengLin, Chen, Min, Lu, Danyi, Wang, Yi, Zhang, Li, Wang, Zhigang, Wu, Baojian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650840/
https://www.ncbi.nlm.nih.gov/pubmed/34887762
http://dx.doi.org/10.3389/fphar.2021.764124