Cargando…

Period 2 Regulates CYP2B10 Expression and Activity in Mouse Liver

CYP2B10 is responsible for metabolism and detoxification of many clinical drugs. Here, we aimed to investigate a potential role of Period 2 (PER2) in regulating expression of hepatic CYP2B10. Regulatory effects of PER2 on hepatic expression of CYP2B10 and other enzymes were determined using Per2-def...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, MengLin, Chen, Min, Lu, Danyi, Wang, Yi, Zhang, Li, Wang, Zhigang, Wu, Baojian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650840/ https://www.ncbi.nlm.nih.gov/pubmed/34887762 http://dx.doi.org/10.3389/fphar.2021.764124

Ejemplares similares

Chronoeffects of the Herbal Medicines Puerariae radix and Coptidis rhizoma in Mice: A Potential Role of REV-ERBα
por: Liu, Jinming, et al.
Publicado: (2021)

Puerariae lobatae radix protects against UVB-induced skin aging via antagonism of REV-ERBα in mice
por: Ma, Luyao, et al.
Publicado: (2022)

CYP2D6 Phenotyping Using Urine, Plasma, and Saliva Metabolic Ratios to Assess the Impact of CYP2D6(∗)10 on Interindividual Variation in a Chinese Population
por: Chen, Rui, et al.
Publicado: (2017)

Genetic variation in the 3′-UTR of CYP1A2, CYP2B6, CYP2D6, CYP3A4, NR1I2, and UGT2B7: potential effects on regulation by microRNA and pharmacogenomics relevance
por: Swart, Marelize, et al.
Publicado: (2014)

A frequent CYP2D6 variant promotes skipping of exon 3 and reduces CYP2D6 protein expression in human liver samples
por: Collins, Joseph M., et al.
Publicado: (2023)

Pathway-Targeted Pharmacogenomics of CYP1A2 in Human Liver
por: Klein, Kathrin, et al.
Publicado: (2010)

Effect of Genetic Variability in the CYP4F2, CYP4F11, and CYP4F12 Genes on Liver mRNA Levels and Warfarin Response
por: Zhang, J. E., et al.
Publicado: (2017)

Inhibitory mechanism of vortioxetine on CYP450 enzymes in human and rat liver microsomes
por: Zhan, Yunyun, et al.
Publicado: (2023)

CYP2D6 Genotype-Based Dose Recommendations for Risperidone in Asian People
por: Cui, Yuanxia, et al.
Publicado: (2020)

Borneol influences the pharmacokinetics of florfenicol through regulation of cytochrome P450 1A2 (CYP1A2), CYP2C11, CYP3A1, and multidrug resistance 1 (MDR1) mRNA expression levels in rats
por: LI, Xuting, et al.
Publicado: (2021)

Regulation of X-Ray Irradiation on the Activity and Expression Levels of CYP1A2 and CYP2E1 in Rats
por: Li, Xiang-Yang, et al.
Publicado: (2020)

The impact of CYP2D6*41 on CYP2D6 enzyme activity using phenotyping methods in urine, plasma, and saliva
por: Jin, Ye, et al.
Publicado: (2022)

CYP2C8 and CYP2C9 mRNA expression profile in the human fetus
por: Johansson, Maria, et al.
Publicado: (2014)

The pharmacogenetics of CYP2D6 and CYP2C19 in a case series of antidepressant responses
por: Kee, Ping Siu, et al.
Publicado: (2023)

Identification and drug metabolic characterization of four new CYP2C9 variants CYP2C9*72-*75 in the Chinese Han population
por: Zhao, Fang-Ling, et al.
Publicado: (2022)

Characterization of complex structural variation in the CYP2D6-CYP2D7-CYP2D8 gene loci using single-molecule long-read sequencing
por: Turner, Amy J., et al.
Publicado: (2023)

Pharmacogenetics of cytochrome P450 2B6 (CYP2B6): advances on polymorphisms, mechanisms, and clinical relevance
por: Zanger, Ulrich M., et al.
Publicado: (2013)

CYP2D7 Sequence Variation Interferes with TaqMan CYP2D6(*)15 and (*)35 Genotyping
por: Riffel, Amanda K., et al.
Publicado: (2016)

CYP2D6 gene polymorphism and apatinib affect the metabolic profile of fluvoxamine
por: Ye, Zhize, et al.
Publicado: (2022)

CYP2A6 and GABRA2 Gene Polymorphisms are Associated With Dexmedetomidine Drug Response
por: Fang, Chao, et al.
Publicado: (2022)

High Fat Diet-Induced Hepatic 18-Carbon Fatty Acids Accumulation Up-Regulates CYP2A5/CYP2A6 via NF-E2-Related Factor 2
por: Wang, Xing-he, et al.
Publicado: (2017)

Developmental Pharmacogenetics of CYP2D6 in Chinese Children: Loratadine as a Substrate Drug
por: Li, Qian, et al.
Publicado: (2021)

Risk assessment and molecular mechanism study of drug-drug interactions between rivaroxaban and tyrosine kinase inhibitors mediated by CYP2J2/3A4 and BCRP/P-gp
por: Zhao, Tingting, et al.
Publicado: (2022)

Prevalence and Accuracy of Information on CYP2D6, CYP2C19, and CYP2C9 Related Substrate and Inhibitor Co-Prescriptions in the General Population: A Cross‐Sectional Descriptive Study as Part of the PharmLines Initiative
por: Bahar, Muh. Akbar, et al.
Publicado: (2020)

Curcumin Successfully Inhibited the Computationally Identified CYP2A6 Enzyme-Mediated Bioactivation of Aflatoxin B1 in Arbor Acres broiler
por: Muhammad, Ishfaq, et al.
Publicado: (2017)

Characterization of 15 CYP2J2 variants identified in the Chinese Han population on the metabolism of ebastine and terfenadine in vitro
por: Zou, Li-Li, et al.
Publicado: (2023)

Identification and Analysis of CYP7A1, CYP17A1, CYP20A1, CYP27A1 and CYP51A1 in Cynomolgus Macaques
por: UNO, Yasuhiro, et al.
Publicado: (2014)

Transcriptome and Lipid Metabolomics-Based Discovery: Glycyrrhizic Acid Alleviates Tripterygium Glycoside Tablet-Induced Acute Liver Injury by Regulating the Activities of CYP and the Metabolism of Phosphoglycerides
por: Shi, Qiaoli, et al.
Publicado: (2022)

Impact of the CYP2D6 Genotype on Metoprolol Tolerance and Adverse Events in Elderly Chinese Patients With Cardiovascular Diseases
por: Chen, Jianqiao, et al.
Publicado: (2022)

Effect of CYP4F2 Polymorphisms on Ticagrelor Pharmacokinetics in Healthy Chinese Volunteers
por: Nie, Shanshan, et al.
Publicado: (2022)

CYP2D6 Reduced Function Variants and Genotype/Phenotype Translations of CYP2D6 Intermediate Metabolizers: Implications for Personalized Drug Dosing in Psychiatry
por: Molden, Espen, et al.
Publicado: (2021)

Triptriolide Alleviates Lipopolysaccharide-Induced Liver Injury by Nrf2 and NF-κB Signaling Pathways
por: Yang, Yi-Qi, et al.
Publicado: (2018)

The impact of CYP2C19 genotype on phenoconversion by concomitant medication
por: de Jong, Laura M., et al.
Publicado: (2023)

Involvement of CYP2E1 in the Course of Brain Edema Induced by Subacute Poisoning With 1,2-Dichloroethane in Mice
por: Jin, Xiaoxia, et al.
Publicado: (2018)

Cyp2j5-Gene Deletion Affects on Acetylcholine and Adenosine-Induced Relaxation in Mice: Role of Angiotensin-II and CYP-Epoxygenase Inhibitor
por: Agba, Stephanie, et al.
Publicado: (2020)

Analysis of Drug Metabolizing Gene Panel in Osteosarcoma Patients Identifies Association Between Variants in SULT1E1, CYP2B6 and CYP4F8 and Methotrexate Levels and Toxicities
por: Hurkmans, Evelien G. E., et al.
Publicado: (2020)

Differential Impact of Nevirapine on Artemether-Lumefantrine Pharmacokinetics in Individuals Stratified by CYP2B6 c.516G>T Genotypes
por: Abdullahi, Sa’ad T., et al.
Publicado: (2020)

Functional Characterization of Human CYP2C9 Allelic Variants in COS-7 Cells
por: Du, Huihui, et al.
Publicado: (2016)

Enzymatic Activities of CYP3A4 Allelic Variants on Quinine 3-Hydroxylation In Vitro
por: Zhou, Xiao-Yang, et al.
Publicado: (2019)

Pharmacokinetics-Based Chronoefficacy of Semen Strychni and Tripterygium Glycoside Tablet Against Rheumatoid Arthritis
por: Lin, Jingpan, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_m64jc8ltoa2s4v2sm1rdhii59p