Cargando…

Human‐Specific Transcriptome of Ventral and Dorsal Midbrain Dopamine Neurons

OBJECTIVE: Neuronal loss in the substantia nigra pars compacta (SNpc) in Parkinson disease (PD) is not uniform, as dopamine neurons from the ventral tier are lost more rapidly than those of the dorsal tier. Identifying the intrinsic differences that account for this differential vulnerability may pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Monzón‐Sandoval, Jimena, Poggiolini, Ilaria, Ilmer, Tobias, Wade‐Martins, Richard, Webber, Caleb, Parkkinen, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8651008/
https://www.ncbi.nlm.nih.gov/pubmed/32167609
http://dx.doi.org/10.1002/ana.25719