Bispecific antibodies targeting distinct regions of the spike protein potently neutralize SARS-CoV-2 variants of concern

The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern threatens the efficacy of existing vaccines and therapeutic antibodies and underscores the need for additional antibody-based tools that potently neutralize variants by targeting multiple sites of the s...

Descripción completa

Detalles Bibliográficos
Autores principales: Cho, Hyeseon, Gonzales-Wartz, Kristina Kay, Huang, Deli, Yuan, Meng, Peterson, Mary, Liang, Janie, Beutler, Nathan, Torres, Jonathan L., Cong, Yu, Postnikova, Elena, Bangaru, Sandhya, Talana, Chloe Adrienna, Shi, Wei, Yang, Eun Sung, Zhang, Yi, Leung, Kwanyee, Wang, Lingshu, Peng, Linghang, Skinner, Jeff, Li, Shanping, Wu, Nicholas C., Liu, Hejun, Dacon, Cherrelle, Moyer, Thomas, Cohen, Melanie, Zhao, Ming, Lee, Frances Eun-Hyung, Weinberg, Rona S., Douagi, Iyadh, Gross, Robin, Schmaljohn, Connie, Pegu, Amarendra, Mascola, John R., Holbrook, Michael, Nemazee, David, Rogers, Thomas F., Ward, Andrew B., Wilson, Ian A., Crompton, Peter D., Tan, Joshua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8651051/
https://www.ncbi.nlm.nih.gov/pubmed/34519517
http://dx.doi.org/10.1126/scitranslmed.abj5413

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8651051/
https://www.ncbi.nlm.nih.gov/pubmed/34519517
http://dx.doi.org/10.1126/scitranslmed.abj5413

Ejemplares similares