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Neurofilament Light (NF-L) Chain Protein from a Highly Polymerized Structural Component of the Neuronal Cytoskeleton to a Neurodegenerative Disease Biomarker in the Periphery

Neurofilaments (NFs) are critical scaffolding components of the axoskeleton of healthy neurons interacting directly with multiple synaptic-phosphoproteins to support and coordinate neuronal cell shape, cytoarchitecture, synaptogenesis and neurotransmission. While neuronal presynaptic proteins such a...

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Detalles Bibliográficos
Autores principales: Zhao, Yuhai, Arceneaux, Lisa, Culicchia, Frank, Lukiw, Walter J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8651065/
https://www.ncbi.nlm.nih.gov/pubmed/34881359
http://dx.doi.org/10.24966/AND-9608/100056