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pdCSM-GPCR: predicting potent GPCR ligands with graph-based signatures

MOTIVATION: G protein-coupled receptors (GPCRs) can selectively bind to many types of ligands, ranging from light-sensitive compounds, ions, hormones, pheromones and neurotransmitters, modulating cell physiology. Considering their role in many essential cellular processes, they are one of the most t...

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Detalles Bibliográficos
Autores principales: Velloso, João Paulo L, Ascher, David B, Pires, Douglas E V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8651072/
https://www.ncbi.nlm.nih.gov/pubmed/34901870
http://dx.doi.org/10.1093/bioadv/vbab031