The DR1-CSE/H(2)S system inhibits renal fibrosis by downregulating the ERK1/2 signaling pathway in diabetic mice

Glomerular mesangial cell (MC) proliferation and extracellular matrix deposition are the main pathological changes in diabetic nephropathy. Hydrogen sulfide (H(2)S) inhibits the proliferation of MCs. Dopamine 1 receptors (DR1) are expressed in MCs and serve important physiological roles. However, it...

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Detalles Bibliográficos
Autores principales: Li, Hongzhu, Sun, Fengqi, Bai, Shuzhi, Chang, Guiquan, Wu, Ren, Wei, Yaxin, Wen, Xin, Xi, Yuxin, Hao, Jinghui, Zaid, Altaany
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8651227/
https://www.ncbi.nlm.nih.gov/pubmed/34779492
http://dx.doi.org/10.3892/ijmm.2021.5062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8651227/
https://www.ncbi.nlm.nih.gov/pubmed/34779492
http://dx.doi.org/10.3892/ijmm.2021.5062

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