Characterization of the endogenous DAF-12 ligand and its use as an anthelmintic agent in Strongyloides stercoralis

A prevalent feature of Strongyloides stercoralis is a life-long and potentially lethal infection that is due to the nematode parasite’s ability to autoinfect and, thereby, self-replicate within its host. Here, we investigated the role of the parasite’s nuclear receptor, Ss-DAF-12, in governing infec...

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Detalles Bibliográficos
Autores principales: Wang, Zhu, Cheong, Mi Cheong, Tsien, Jet, Deng, Heping, Qin, Tian, Stoltzfus, Jonathan DC, Jaleta, Tegegn G, Li, Xinshe, Lok, James B, Kliewer, Steven A, Mangelsdorf, David J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Microbiology and Infectious Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8651287/
https://www.ncbi.nlm.nih.gov/pubmed/34874004
http://dx.doi.org/10.7554/eLife.73535

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8651287/
https://www.ncbi.nlm.nih.gov/pubmed/34874004
http://dx.doi.org/10.7554/eLife.73535

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