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Pathogen invasion-dependent tissue reservoirs and plasmid-encoded antibiotic degradation boost plasmid spread in the gut

Many plasmids encode antibiotic resistance genes. Through conjugation, plasmids can be rapidly disseminated. Previous work identified gut luminal donor/recipient blooms and tissue-lodged plasmid-bearing persister cells of the enteric pathogen Salmonella enterica serovar Typhimurium (S.Tm) that survi...

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Detalles Bibliográficos
Autores principales: Bakkeren, Erik, Herter, Joana Anuschka, Huisman, Jana Sanne, Steiger, Yves, Gül, Ersin, Newson, Joshua Patrick Mark, Brachmann, Alexander Oliver, Piel, Jörn, Regoes, Roland, Bonhoeffer, Sebastian, Diard, Médéric, Hardt, Wolf-Dietrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8651294/
https://www.ncbi.nlm.nih.gov/pubmed/34872631
http://dx.doi.org/10.7554/eLife.69744