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Pathogen invasion-dependent tissue reservoirs and plasmid-encoded antibiotic degradation boost plasmid spread in the gut
Many plasmids encode antibiotic resistance genes. Through conjugation, plasmids can be rapidly disseminated. Previous work identified gut luminal donor/recipient blooms and tissue-lodged plasmid-bearing persister cells of the enteric pathogen Salmonella enterica serovar Typhimurium (S.Tm) that survi...
Autores principales: | Bakkeren, Erik, Herter, Joana Anuschka, Huisman, Jana Sanne, Steiger, Yves, Gül, Ersin, Newson, Joshua Patrick Mark, Brachmann, Alexander Oliver, Piel, Jörn, Regoes, Roland, Bonhoeffer, Sebastian, Diard, Médéric, Hardt, Wolf-Dietrich |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8651294/ https://www.ncbi.nlm.nih.gov/pubmed/34872631 http://dx.doi.org/10.7554/eLife.69744 |
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