miR-15a-3p Protects Against Isoniazid-Induced Liver Injury via Suppressing N-Acetyltransferase 2 Expression

Isoniazid (INH), an effective first-line drug for tuberculosis treatment, has been reported to be associated with hepatotoxicity for decades, but the underlying mechanisms are poorly understood. N-acetyltransferase 2 (NAT2) is a Phase II enzyme that specifically catalyzes the acetylation of INH, and...

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Detalles Bibliográficos
Autores principales: Li, Xinmei, Zhang, Heng, Xu, Lin, Jin, Yuan, Luo, Jiao, Li, Chuanhai, Zhao, Kunming, Zheng, Yuxin, Yu, Dianke, Zhao, Yanjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8651391/
https://www.ncbi.nlm.nih.gov/pubmed/34888351
http://dx.doi.org/10.3389/fmolb.2021.752072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8651391/
https://www.ncbi.nlm.nih.gov/pubmed/34888351
http://dx.doi.org/10.3389/fmolb.2021.752072

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