A d-2-hydroxyglutarate biosensor based on specific transcriptional regulator DhdR

d-2-Hydroxyglutarate (d-2-HG) is a metabolite involved in many physiological metabolic processes. When d-2-HG is aberrantly accumulated due to mutations in isocitrate dehydrogenase or d-2-HG dehydrogenase, it functions in a pro-oncogenic manner and is thus considered a therapeutic target and biomark...

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Detalles Bibliográficos
Autores principales: Xiao, Dan, Zhang, Wen, Guo, Xiaoting, Liu, Yidong, Hu, Chunxia, Guo, Shiting, Kang, Zhaoqi, Xu, Xianzhi, Ma, Cuiqing, Gao, Chao, Xu, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8651671/
https://www.ncbi.nlm.nih.gov/pubmed/34876568
http://dx.doi.org/10.1038/s41467-021-27357-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8651671/
https://www.ncbi.nlm.nih.gov/pubmed/34876568
http://dx.doi.org/10.1038/s41467-021-27357-7

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