Factor quinolinone inhibitors alter cell morphology and motility by destabilizing interphase microtubules

Factor quinolinone inhibitors are promising anti-cancer compounds, initially characterized as specific inhibitors of the oncogenic transcription factor LSF (TFCP2). These compounds exert anti-proliferative activity at least in part by disrupting mitotic spindles. Herein, we report additional interph...

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Detalles Bibliográficos
Autores principales: Stoiber, Patrick, Scribani Rossi, Pietro, Pokharel, Niranjana, Germany, Jean-Luc, York, Emily A., Schaus, Scott E., Hansen, Ulla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8651680/
https://www.ncbi.nlm.nih.gov/pubmed/34876605
http://dx.doi.org/10.1038/s41598-021-02962-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8651680/
https://www.ncbi.nlm.nih.gov/pubmed/34876605
http://dx.doi.org/10.1038/s41598-021-02962-0

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