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Runx1 protects against the pathological progression of osteoarthritis

Runt-related transcription factor-1 (Runx1) is required for chondrocyte-to-osteoblast lineage commitment by enhancing both chondrogenesis and osteogenesis during vertebrate development. However, the potential role of Runx1 in joint diseases is not well known. In the current study, we aimed to explor...

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Detalles Bibliográficos
Autores principales: Zhou, Chenchen, Cui, Yujia, Yang, Yueyi, Guo, Daimo, Zhang, Demao, Fan, Yi, Li, Xiaobing, Zou, Jing, Xie, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8651727/
https://www.ncbi.nlm.nih.gov/pubmed/34876557
http://dx.doi.org/10.1038/s41413-021-00173-x