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Oxidative stress-induced FABP5 S-glutathionylation protects against acute lung injury by suppressing inflammation in macrophages

Oxidative stress contributes to the pathogenesis of acute lung injury. Protein S-glutathionylation plays an important role in cellular antioxidant defense. Here we report that the expression of deglutathionylation enzyme Grx1 is decreased in the lungs of acute lung injury mice. The acute lung injury...

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Detalles Bibliográficos
Autores principales: Guo, Yuxian, Liu, Yaru, Zhao, Shihao, Xu, Wangting, Li, Yiqing, Zhao, Pengwei, Wang, Di, Cheng, Hongqiang, Ke, Yuehai, Zhang, Xue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8651733/
https://www.ncbi.nlm.nih.gov/pubmed/34876574
http://dx.doi.org/10.1038/s41467-021-27428-9